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Santor Barkhordari one Mohr vije

$596.00
$586.00

10 in stock

10 in stock

Description

The Santoor is an Instrument with approximately 100 strings which originated in the Himalayan Valley of Kashmir. Originally known as “Shata Tantri Veena” (Sanskrit version of one hundred strings), which has close relatives in British and American “Hammer Dulcimer”, Chinese “Yang Chin” and the east European “Cimbalom”. Santoor, which originated from Vedic “Vana Veena”, is characteristic of Kashmir Valley and is neither seen or played any where played. The “Vana Veena” also had strings and was played with sticks. In the orient the fundamentals of this instrument is no doubt very ancient. It seems that the origin goes back to Assyrians and Babylonians. An instrument, which at the same breath could give the audiences a feel of melody and rhythm naturally, had much to offer in terms of musicality. The emergence of Santoor as a popular Indian classical instrument has of course been due to the presence of stalwart Pandit Shiv Kumar Sharma. However, its roots are necessarily from the Durbars of Sufi heretics of Kashmir, where its folk origins were interspersed with Hindustani classical music.

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ContentThe Santoor is an Instrument with approximately 100 strings which originated in the Himalayan Valley of Kashmir. Originally known as “Shata Tantri Veena” (Sanskrit version of one hundred strings), which has close relatives in British and American “Hammer Dulcimer”, Chinese “Yang Chin” and the east European “Cimbalom”. Santoor, which originated from Vedic “Vana Veena”, is characteristic of Kashmir Valley and is neither seen or played any where played. The “Vana Veena” also had strings and was played with sticks. In the orient the fundamentals of this instrument is no doubt very ancient. It seems that the origin goes back to Assyrians and Babylonians. An instrument, which at the same breath could give the audiences a feel of melody and rhythm naturally, had much to offer in terms of musicality. The emergence of Santoor as a popular Indian classical instrument has of course been due to the presence of stalwart Pandit Shiv Kumar Sharma. However, its roots are necessarily from the Durbars of Sufi heretics of Kashmir, where its folk origins were interspersed with Hindustani classical music.Persian tar is a long necked, double-bowl body instrument. Persian Tar is a string or stringed instrument. It is the newest musical instrument of Persian folklor. It only dates back to 250 years ago. It's current form was developed in the 18th century. Iranians say that Tar is the sultan of instruments. It is strongly believed that Tar is the descendent of rubab which is played in Pakistan and Afghanistan. After is has been adopted to Persian art by the musicians it became a common urban instrument. The long and narrow neck of Tar has a flat fingerboard which ends with six wooden pegs. It has three courses of double "singing" strings which lies on the fingerboard There are also two pairs of shorter strings which is under the bass and over two small copper bridges on the upper side of the fingerboard. Tuning of these strings are variable according to the performer's taste.Setar is a string or stringed instrument. In these musical instruments a stretched vibrating string produces the initial sound. They are called Chordophones as well. "Setâr" consists of "Se" and "Târ". The word "Târ" means string and the word "Se" means three in Persian and for this reason "Setâr" means a stringed instrument with three strings. Setar is a plucked string instrument and and the right index finger nail is used as a plectrum to pluck or strum the instrument. Setar is a fretted string instrument, thus the instrument has frets that have been tied on the neck. Setar is one of the main instruments of Persian art music.The setar is a Persian (Iranian) stringed instrument with a small, pear-shaped soundbox and four metal strings. Its name means “three strings.” A fourth drone string was added about 150 years ago by the mystic Moshtagh Ali Shah. The drone string is referred to as the “Sim Moshtagh” (Moshtagh string) by many prominent tar and setar players. This modification gave the delicate instrument a “bigger” sound and more complex tuning possibilities. The resonating box of the setar is attached to a long neck that has twenty-five gut frets. The soundbox is made from mulberry wood, while the neck comes from the walnut tree. The instrument has a melodic range of just over twenty scale degrees. Although it is traditionally played with the right index finger’s nail, in the past three decades, two distinguished master performers, Mohammad-Reza Lotfi and Hossein Alizadeh, have introduced new techniques to give setar playing a whole new life. Albumin is an appealing carrier in nanomedicine because of its unique features. First, it is the most abundant protein in plasma, endowing high biocompatibility, biodegradability, nonimmunogenicity, and safety for its clinical application. Second, albumin chemical structure and conformation allows interaction with many different drugs, potentially protecting them from elimination and metabolism in vivo, thus improving their pharmacokinetic properties. Finally, albumin can interact with receptors overexpressed in many diseased tissues and cells, providing a unique feature for active targeting of the disease site without the addition of specific ligands to the nanocarrier. For this reason, albumin, characterized by an extended serum half-life of around 19 days, has the potential of promoting half-life extension and targeted delivery of drugs. Therefore, this article focuses on the importance of albumin as a nanodrug delivery carrier for hydrophobic drugs, taking advantage of the passive as well as active targeting potential of this nanocarrier. Particular attention is paid to the breakthrough NAB-Technology, with emphasis on the advantages of Nab-Paclitaxel (Abraxane), compared to the solvent-based formulations of Paclitaxel, i.e., CrEL-paclitaxel (Taxol) in a clinical setting. Finally, the role of albumin in carrying anticancer compounds is depicted, with a particular focus on the albumin-based formulations that are currently undergoing clinical trials. The article sheds light on the power of an endogenous substance, such as albumin, as a drug delivery system, signifies the importance of the drug vehicle in drug performance in the biological systems, and highlights the possible future trends in the use of this drug delivery system.
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